Hannu Uusitalo Selected Research

Guanine Nucleotide Dissociation Inhibitors (GDIs)

8/2015	Matrix metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-9, and TIMP-1, TIMP-2 and TIMP-3) and markers for vascularization in functioning and non-functioning bleb capsules of glaucoma drainage implants.
9/2014	Immunohistochemical analysis of extracellular matrix bleb capsules of functioning and non-functioning glaucoma drainage implants.

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Hannu Uusitalo Research Topics

Disease

19	Glaucoma 05/2022 - 07/2005
9	Open-Angle Glaucoma (Glaucoma, Open Angle) 06/2017 - 03/2007
8	Exfoliation Syndrome 06/2017 - 02/2007
7	Inflammation (Inflammations) 11/2020 - 05/2008
6	Dry Eye Syndromes (Dry Eye Syndrome) 12/2022 - 05/2010
6	Macular Degeneration (Age-Related Maculopathy) 09/2020 - 07/2005
4	Ocular Hypertension (Glaucoma, Suspect) 12/2014 - 02/2010
3	Myopia 01/2018 - 03/2002
2	Vision Disorders (Hemeralopia) 01/2021 - 02/2020
2	Refractive Errors (Refractive Error) 01/2020 - 01/2010
2	Hypoxia (Hypoxemia) 01/2018 - 01/2018
2	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2018 - 09/2016
2	Hyperemia 01/2018 - 01/2016
2	Retinal Degeneration 01/2017 - 06/2005
2	Blepharitis 01/2016 - 05/2010
2	Pruritus (Itching) 01/2016 - 05/2010
2	Foreign Bodies (Foreign Body) 01/2016 - 05/2010
2	Blister (Bulla) 08/2015 - 09/2014
2	Atrophy 01/2015 - 01/2013
2	Atherosclerosis 01/2013 - 03/2007
2	Ganglion Cysts (Ganglion) 12/2010 - 05/2009
2	Hypertension (High Blood Pressure) 10/2007 - 01/2007
1	Pseudoxanthoma Elasticum (Gronblad Strandberg Syndrome) 01/2022
1	Cataract (Cataracts) 01/2021
1	Presbyopia 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2020
1	Osteoarthritis 09/2020
1	Parkinson Disease (Parkinson's Disease) 09/2020
1	Hyperopia (Hypermetropia) 01/2019
1	Strabismus (Squint) 01/2019
1	Gliosis 01/2019
1	Amblyopia (Lazy Eye) 01/2018
1	Astigmatism 01/2018
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Retinal Vein Occlusion 01/2018
1	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2018
1	Obesity 01/2016
1	Eye Diseases (Eye Disease) 02/2015

Drug/Important Bio-Agent (IBA)

8	Retinaldehyde (Retinal)IBA 01/2021 - 08/2006
6	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2017
6	tafluprostIBA 01/2018 - 02/2010
5	Pharmaceutical PreparationsIBA 12/2022 - 12/2006
5	Timolol (Blocadren)FDA LinkGeneric 05/2022 - 07/2005
5	Latanoprost (Xalatan)FDA Link 01/2018 - 02/2010
5	ProstaglandinsIBA 01/2016 - 01/2008
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2007
3	CalciumIBA 06/2017 - 03/2007
3	Ophthalmic Solutions (Eye Drops)IBA 01/2016 - 11/2006
3	Matrix Metalloproteinases (MMPs)IBA 08/2015 - 05/2007
3	Capsules (Microcapsules)IBA 08/2015 - 03/2009
3	Retinal Pigments (Pigments, Visual)IBA 09/2009 - 06/2005
3	HydrogelsIBA 11/2006 - 07/2005
2	Oxygen (Dioxygen)IBA 01/2018 - 01/2018
2	Fluorescein (Funduscein)FDA LinkGeneric 01/2016 - 05/2010
2	Guanine Nucleotide Dissociation Inhibitors (GDIs)IBA 08/2015 - 09/2014
2	Phospholipases A2 (Phospholipase A2)IBA 05/2008 - 03/2007
2	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 10/2007 - 02/2007
1	brinzolamide (Azopt)FDA Link 05/2022
1	diphosphoric acid (pyrophosphoric acid)IBA 01/2022
1	trabecular meshwork-induced glucocorticoid response proteinIBA 07/2021
1	ORALIT (ORS)IBA 07/2021
1	Mitochondrial DNA (mtDNA)IBA 11/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020
1	afliberceptIBA 02/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2020
1	Bevacizumab (Avastin)FDA Link 02/2020
1	tear proteinsIBA 01/2019
1	Crystallins (Crystallin)IBA 01/2018
1	Fluorometholone (FML)FDA Link 01/2018
1	Fluoxetine (Prozac)FDA LinkGeneric 01/2018
1	SteroidsIBA 01/2018
1	ProteomeIBA 01/2018
1	Nonmuscle Myosin Type IIAIBA 01/2018
1	FurinIBA 01/2018
1	FilaminsIBA 01/2018
1	oxidized low density lipoproteinIBA 06/2017
1	LipidsIBA 06/2017
1	Human Serum Albumin FDA LinkGeneric 09/2016
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 09/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	Tissue Inhibitor of Metalloproteinase-2IBA 08/2015
1	Phenobarbital (Luminal)FDA Link 08/2015
1	Tissue Inhibitor of Metalloproteinase-1IBA 08/2015
1	Tissue Inhibitor of Metalloproteinase-3IBA 08/2015
1	Laminin (Merosin)IBA 09/2014
1	Collagen Type IV (Type IV Collagen)IBA 09/2014
1	Fibronectins (Fibronectin)IBA 09/2014

Therapy/Procedure

4	Laser In Situ Keratomileusis (LASIK) 01/2020 - 01/2010
4	Therapeutics 01/2018 - 12/2006
3	Lasers (Laser) 01/2020 - 01/2010
2	Injections 02/2020 - 11/2016
2	Intravitreal Injections 02/2020 - 05/2009
2	Refractive Surgical Procedures 01/2020 - 01/2019
2	Glaucoma Drainage Implants 08/2015 - 09/2014
2	Topical Administration 08/2007 - 12/2006
2	Photorefractive Keratectomy 03/2004 - 03/2002
1	Trabeculectomy (Trabeculoplasty) 03/2021
1	Multifocal Intraocular Lenses 01/2021
1	Castration 01/2018